Leguizamón started his career in Gimnasia y Esgrima de Concepción del Uruguay. He then moved on to River Plate. Not having played much at River, he was loaned to Unión de Santa Fe and Polideportivo Ejido (Spain). Subsequently, he joined Talleres de Córdoba where he fought unsuccessfully to get the team’s promotion to Argentine Primera División. He then played for Gimnasia y Esgrima de La Plata between 2006 and 2007.